By George A Parker,Catherine A. Picut

Atlas of Histology of the Juvenile Rat could be of curiosity to toxicologic pathologists, toxicologists, and different organic scientists who're drawn to the histomorphology of youth rats. For a number of many years the laboratory rat has been used largely in nonclinical toxicology reports designed to notice strength human toxicity of substances, agrochemicals, business chemical compounds, and environmental dangers. those experiences commonly have concerned younger grownup rats which are 8-10 weeks of age as experiences are all started. it really is turning into more and more obvious that kids and younger animals can have various responses to drug/chemical exposures, for this reason, regulatory businesses are emphasizing toxicology experiences in juvenile animals.

While the histologic beneficial properties of organs from younger grownup and elderly laboratory rats are renowned, much less is understood in regards to the histologic positive aspects of organs from juvenile rats. ultimate histologic adulthood of many organs is completed postnatally, therefore immature histologic positive aspects has to be distinct from chemical- or drug-related results. whereas this postnatal organ improvement is understood to exist as a basic idea, specific information about postnatal histologic improvement isn't available. The Atlas contains organs which are more often than not sampled in nonclinical toxicology reports and offers the histologic positive aspects at weekly durations, beginning at delivery and lengthening via postnatal day 42.

  • Written and edited through hugely skilled, board-certified toxicologic pathologists
  • Includes greater than seven-hundred high-resolution microscopic pictures from organs which are usually tested in security evaluation toxicology studies
  • Detailed determine legends and bankruptcy narratives current the salient gains of every organ at at any time when interval
  • Figures can be found for additional research through Elsevier’s digital Microscope, which permits viewing of microscopic photos at better magnification
  • Valuable source for toxicologic pathologists who're faced with interpretation of lesions in juvenile rats in events the place age-matched concurrent controls aren't to be had for comparability, e.g., with unscheduled decedents
  • Figures can be found for additional examine on ScienceDirect with digital Microscope, which permits viewing of microscopic photos at larger magnification

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Atlas of Histology of the Juvenile Rat by George A Parker,Catherine A. Picut

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