By David Phillips

Biochemistry of Platelets is a entire overview of the biochemistry of platelets, with emphasis at the molecular foundation for many of the organic procedures during which they take part. themes diversity from stimulus-response coupling mechanisms to platelet contractile proteins, platelet membrane glycoproteins, and garage organelles in platelets and megakaryocytes. The expression and serve as of adhesive proteins at the platelet floor is additionally discussed.

Comprised of 12 chapters, this e-book starts with an outline of the morphological and metabolic responses to agonists, in addition to the involvement of definite procedures within the coupling of agonist-receptor interactions to platelet responses. the subsequent bankruptcy offers with platelet arachidonate metabolism and platelet-activating issue, concentrating on the discharge of arachidonate from platelet lipid shops; pathways of platelet arachidonate metabolism and results of arachidonate metabolites; and inhibition of platelet arachidonate metabolism via aspirin. The constitution, functionality, and amendment in ailment of platelet membrane glycoproteins are then mentioned, besides prothrombin activation on platelets and platelet legislation of thrombus formation. Secreted platelet proteins as markers for pathological issues also are considered.

This monograph is meant as a reference for investigators concerned about platelet examine in addition to a resource of data for these operating in different parts of organic investigation.

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Biochemistry of Platelets by David Phillips

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