By Kiyohiko Sugano

A finished advent to utilizing modeling and simulation courses in drug discovery and development

Biopharmaceutical modeling has develop into crucial to the layout and improvement of latest medicines. Influencing key features of the improvement strategy, together with drug substance layout, formula layout, and toxicological publicity evaluate, biopharmaceutical modeling is now noticeable because the linchpin to a drug's destiny luck. And whereas there are various commercially to be had software program courses for drug modeling, there has now not been a unmarried source guiding pharmaceutical execs to the particular instruments and practices had to layout and try out secure drugs.

A advisor to the fundamentals of modeling and simulation courses, Biopharmaceutics Modeling and Simulations bargains pharmaceutical scientists the keys to figuring out how they paintings and are utilized in developing medicinal drugs with wanted medicinal houses. starting with a spotlight at the oral absorption of gear, the ebook discusses:

  • The imperative dogma of oral drug absorption (the interaction of dissolution, solubility, and permeability of a drug), which kinds the foundation of the biopharmaceutical class process (BCS)
  • The proposal of drug concentration
  • How to simulate key drug absorption processes
  • The physiological and drug estate facts used for biopharmaceutical modeling
  • Reliable practices for reporting results

With over two hundred figures and illustrations and a peerless exam of the entire key features of drug research—including operating and examining versions, validation, and compound and formula selection—this reference seamlessly brings jointly the confirmed functional techniques necessary to constructing the secure and powerful drugs of tomorrow.

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Biopharmaceutics Modeling and Simulations: Theory, Practice, Methods, and Applications by Kiyohiko Sugano

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