By Li-He Zhang,Zhen Xi,Jyoti Chattopadhyaya,Sidney M. Hecht

Complete, updated assurance of the wide quarter of nucleic acid chemistry and biology

Assembling contributions from a set of authors with services in all components of nucleic acids, medicinal chemistry, and healing functions, Medicinal Chemistry of Nucleic Acids offers a radical evaluate of nucleic acid chemistry—a speedily evolving and hugely demanding self-discipline without delay accountable for the advance of antiviral and antitumor medicinal drugs. This trustworthy source delves right into a multitude of topic parts concerning the examine of nucleic acids—such because the new advances in genome sequencing, and the methods for developing RNA interference (RNAi) established drugs—to help pharmaceutical researchers in removal roadblocks that prevent their skill to foretell drug efficacy. supplying the newest state-of-the-art technological know-how during this growing to be box, Medicinal Chemistry of Nucleic Acids includes:

  • In-depth assurance of the improvement and alertness of converted nucleosides and nucleotides in medicinal chemistry

  • A shut examine a wide range of present themes on nucleic acid chemistry and biology

  • Essential info at the use of nucleic acid medicinal drugs to regard illnesses like cancer

  • A thorough exploration of siRNA for RNAi and the rules of microRNA, non-coding RNA (ncRNA), a newly constructing and intriguing examine area

Thorough in its technique and promising in its message, Medicinal Chemistry of Nucleic Acids probes the hot domain names of pharmaceutical research—and exposes readers to a wealth of recent drug discovery possibilities rising within the dynamic box of nucleic acid chemistry.

Show description

Read or Download Medicinal Chemistry of Nucleic Acids (Wiley Series in Drug Discovery and Development) PDF

Best pharmacology books

Download e-book for kindle: Combination Products: Regulatory Challenges and Successful by Smita Gopalaswamy,Venky Gopalaswamy

The sphere of mixture product improvement (products born of the mixing of clinical units, biologics, and medicine) is so new that, whereas literature abounds on each one half separately, there are only a few courses, together with FDA records, to be had about the specified demanding situations posed by means of this nascent yet fast-growing quarter.

Get Apicomplexan Parasites: Molecular Approaches toward Targeted PDF

This guide is the 1st facing the invention of gear directed opposed to apicomplexan parasites. among others, this team of endoparasites contains the causative brokers of Malaria, Toxoplasmosis, and Babesiosis, the latter taking place often in animals. Written by way of well known medical specialists from academia and undefined, the publication specializes in currentdrug improvement techniques for all apicomplexan ailments making it beautiful to a wide viewers, starting from learn labs in academia to the human and veterinarian pharmaceutical undefined.

Download e-book for kindle: Assessing Bioavailablility of Drug Delivery Systems: by Jean-Maurice Vergnaud,Iosif-Daniel Rosca

Exploring easy methods to practice in vitro/in vivo correlations for managed liberate dosage types, Bioavailability of Drug supply structures: Mathematical Modeling truly elucidates this complicated phenomena and gives a advisor for the respective mathematical modeling. The ebook introduces mathematical modeling equipment for calculating the profiles of plasma degrees bought with managed liberate dosage varieties and offers examples and case reviews to demonstrate the innovations hired.

Download e-book for iPad: Global Virology I - Identifying and Investigating Viral by Paul Shapshak,John T. Sinnott,Charurut Somboonwit,Jens H.

This e-book presents trajectories and illustrations of viruses that experience catapulted into the worldwide area (linked to people, animals, and vectors) as a result of human behaviors lately, in addition to viruses that experience already proven enlargement between people, animals, and vectors quite a few a long time in the past. issues within the present publication contain: vaccinesenvironmental impactemerging virus transmissionFilovirus (Ebola)hemorrhagic feversflavivirusesDengue evasionpapillomavirusesHepatitis CNipah virusgiant viruseshantavirusesbunyavirusesencephalitidesWest Nile virusZika virusXMRVhenipaviruseshuman breathing syncytial virusinfluenza A virusseveral facets of HIV-1

Additional resources for Medicinal Chemistry of Nucleic Acids (Wiley Series in Drug Discovery and Development)

Example text

Download PDF sample

Medicinal Chemistry of Nucleic Acids (Wiley Series in Drug Discovery and Development) by Li-He Zhang,Zhen Xi,Jyoti Chattopadhyaya,Sidney M. Hecht


by Anthony
4.1

Rated 4.13 of 5 – based on 39 votes