By Friedlieb Pfannkuch,Laura Suter-Dick

adapted to the wishes of scientists constructing medicinal drugs, chemical substances, cosmetics and different items this one-stop reference for medicinal chemists covers all of the most recent advancements within the box of predictive toxicology and its purposes in protection assessment.

With a willing emphasis on novel techniques, the subjects were tackled through chosen specialist scientists, who're accustomed to the theoretical clinical historical past in addition to with the sensible software of present tools. rising applied sciences in toxicity evaluation are brought and evaluated when it comes to their predictive energy, with separate sections on laptop predictions and simulation equipment, novel in vitro platforms together with these making use of stem cells, toxicogenomics and novel biomarkers. In every one case, the main promising tools are mentioned and in comparison to classical in vitro and in vivo toxicology assays. ultimately, an outlook part discusses such forward-looking subject matters as immunotoxicology evaluate and novel regulatory requirements.

With its wealth of methodological wisdom and its severe overview of recent techniques, this can be a important advisor for toxicologists operating in pharmaceutical improvement, in addition to in security review and the rules of gear and chemicals.

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Predictive Toxicology: From Vision to Reality, Volume 64 (Methods and Principles in Medicinal Chemistry) by Friedlieb Pfannkuch,Laura Suter-Dick

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